Gastrin anticorps (full length)

N° du produit ABIN7878262

Cet anticorps anti-Gastrin Monoclonal Souris (Clone GAST-2635) (ABIN7878262) détecte spécifiquement Gastrin dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Gastrin anticorps (full length) (ABIN7878262)

Antigène: Gastrin (GAST)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Gastrin est non-conjugé

Application: ELISA

Classe de qualité: Carrier-free

Clone: GAST-2635

Détail du produit anti-Gastrin anticorps

Épitope: full length

Fonction: Gastrin Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant full-length human GAST protein was used as the immunogen for this Gastrin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Gastrin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Gastrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Gastrin

Antigène: Gastrin (GAST)

Autre désignation: Gastrin

Sujet: Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.

UniProt: P01350