Recombinant CGA anticorps (full length)

N° du produit ABIN7878307

Cet anticorps anti-CGA Monoclonal Souris (Clone rCHGA-9612) (ABIN7878307) détecte spécifiquement CGA dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant CGA anticorps (full length) (ABIN7878307)

Antigène: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CGA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RCHGA-9612

Détail du produit anti-CGA anticorps

Épitope: full length

Fonction: Recombinant CgA Antibody / Chromogranin A

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human Chromogranin A protein was used as the immunogen for the recombinant CgA antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CgA antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant CgA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CGA

Antigène: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Autre désignation: CgA

Sujet: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

UniProt: P10645

Pathways: Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism