GLG1 anticorps (full length)

N° du produit ABIN7878314

Cet anticorps Souris Monoclonal détecte spécifiquement GLG1 dans IHC (fp) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GLG1 anticorps (full length) (ABIN7878314)

Antigène: GLG1 (Golgi Glycoprotein 1 (GLG1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLG1 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Classe de qualité: Carrier-free

Clone: GLG1-4830

Détail du produit anti-GLG1 anticorps

Épitope: full length

Fonction: GLG1 Antibody / Golgi Glycoprotein 1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the GLG1 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the GLG1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the GLG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GLG1

Antigène: GLG1 (Golgi Glycoprotein 1 (GLG1))

Autre désignation: GLG1

Sujet: This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.

UniProt: Q92896