GPN1 anticorps (full length)

N° du produit ABIN7878317

Cet anticorps Souris Monoclonal détecte spécifiquement GPN1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GPN1 anticorps (full length) (ABIN7878317)

Antigène: GPN1 (GPN-Loop GTPase 1 (GPN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: GPN1-2350

Détail du produit anti-GPN1 anticorps

Épitope: full length

Fonction: XAB1 Antibody / GPN1

Purification: Protein G affinity chromatography

Immunogène: Recombinant full length human protein was used as the immunogen for this XAB1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the XAB1 antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the XAB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur GPN1

Antigène: GPN1 (GPN-Loop GTPase 1 (GPN1))

Autre désignation: XAB1

Sujet: GPN1 (GPN-loop GTPase 1), also called XAB1 (XPA-binding protein 1) is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating it in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that it has possible GTPase activity.

UniProt: Q9HCN4