HDAC7 anticorps (full length)

N° du produit ABIN7878382

Cet anticorps anti-HDAC7 Monoclonal Souris (Clone PCRP-HDAC7-1B6) (ABIN7878382) détecte spécifiquement HDAC7 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HDAC7 anticorps (full length) (ABIN7878382)

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HDAC7 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: PCRP-HDAC7-1B6

Détail du produit anti-HDAC7 anticorps

Épitope: full length

Fonction: HDAC7 Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the HDAC7 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HDAC7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the HDAC7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur HDAC7

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Autre désignation: HDAC7

Sujet: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Mammalian HDAC7 is a histone deacetylase that interacts with the adaptor mSin3A. The interaction of HDAC7 with mSin3A suggests the association of multiple repression complexes of transcription factors.

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development