Cet anticorps anti-Cytokeratin 13 Monoclonal Souris (Clone KRT13-2659) (ABIN7878478) détecte spécifiquement Cytokeratin 13 dans IF, IHC (p) et FACS.
L’anticorps est réactif avec des échantillons de Humain.
Optimal dilution of the Cytokeratin 13 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the Cytokeratin 13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Antigène
Cytokeratin 13 (KRT13)
(Keratin 13 (KRT13))
Autre désignation
Cytokeratin 13
Sujet
Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.