KRT8 anticorps (full length)

N° du produit ABIN7878518

Cet anticorps Souris Monoclonal détecte spécifiquement KRT8 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour KRT8 anticorps (full length) (ABIN7878518)

Antigène: KRT8 (Keratin 8 (KRT8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: KRT8-2115

Détail du produit anti-KRT8 anticorps

Épitope: full length

Fonction: Cytokeratin 8 Antibody / KRT8 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant full-length human KRT8 protein was used as the immunogen for this Cytokeratin 8 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Cytokeratin 8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Cytokeratin 8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur KRT8

Antigène: KRT8 (Keratin 8 (KRT8))

Autre désignation: Cytokeratin 8

Sujet: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast.

UniProt: P05787