Recombinant L1CAM anticorps (full length)

N° du produit ABIN7878529

Cet anticorps anti-L1CAM Monoclonal Souris (Clone rL1CAM-9163) (ABIN7878529) détecte spécifiquement L1CAM dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant L1CAM anticorps (full length) (ABIN7878529)

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RL1CAM-9163

Détail du produit anti-L1CAM anticorps

Épitope: full length

Fonction: Recombinant L1CAM Antibody / CD171 / NCAM-L1

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human L1CAM protein was used as the immunogen for the recombinant L1CAM antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant L1CAM antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant L1CAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: L1CAM

Sujet: L1 (L1 cell adhesion molecule) also known as CAML1, CD171, and HSAS is an adhesion molecule which plays an important role in the nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). This mouse monoclonal antibody recognizes the sequence immediately NH2-terminal to the tyrosine-based motif and binds L1 only when Y1176 is dephosphorylated. Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.

UniProt: P32004

Pathways: Synaptic Membrane