MLX anticorps (full length)

N° du produit ABIN7878588

L’anticorps anti-MLX Monoclonal Souris est utilisé pour la détection de MLX dans des échantillons de Humain. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour MLX anticorps (full length) (ABIN7878588)

Antigène: MLX (MAX-Like Protein X (MLX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MLX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: PCRP-MLX-1G8

Détail du produit anti-MLX anticorps

Épitope: full length

Fonction: MLX Antibody / Max-like protein X (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human MLX protein was used as the immunogen for the MLX antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the MLX antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the MLX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MLX

Antigène: MLX (MAX-Like Protein X (MLX))

Autre désignation: MLX

Sujet: Max is a nuclear localized bHLH-Zip protein that forms homodimers or heterodimers with Myc family members, including Myc, Mad1, Mad3, Mad4, Mxi1 and Mnt (or Rox). These dimers bind to the E-box sequence CACGTG in order to regulate cell growth, proliferation and apoptosis. Mlx (Max-like protein X) is a bHLH-Zip protein that is structurally and functionally related to Max. Like Max, Mlx is broadly expressed in many tissues and has a long half-life. Mlx also forms homodimers or heterodimers with members of the Myc family, specifically Mad1, Mad4 and Rox, and members of the Mondo family, to repress or activate transcription from CACGTG E-boxes. MondoA forms weak homodimers and preferentially forms heterodimers with Mlx. The MondoA/Mlx complex is primarily localized to the cytoplasm, but will translocate to the nucleus in response to leptomycin B. Mlx can also dimerize with WBSCR14, a protein involved in Williams-Beuren syndrome (WBS), to repress E-box transcription, which provides further evidence that Mlx is a critical element in a transcription factor network.

UniProt: Q9UH92