MED22 anticorps (full length)
Aperçu rapide pour MED22 anticorps (full length) (ABIN7878592)
Antigène
Voir toutes MED22 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- MED22 Antibody (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant full-length human protein was used as the immunogen for the MED22 antibody.
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Isotype
- IgG2b
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Indications d'application
- Optimal dilution of the MED22 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the MED22 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MED22 (Mediator Complex Subunit 22 (MED22))
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Autre désignation
- MED22
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Sujet
- Med22 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. Functioning as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, the mediator complex is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Med22 (mediator complex subunit 22), also known as SURF5 (surfeit locus protein 5), is a ubiquitously expressed 200 amino acid nuclear protein that is one of several components of the mediator complex. There are two isoforms of Med22 that are produced as a result of alternative splicing events.
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UniProt
- Q15528
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Antigène
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