MUC16 anticorps (full length)

N° du produit ABIN7878639

L’anticorps anti-MUC16 Monoclonal Souris est utilisé pour la détection de MUC16 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour MUC16 anticorps (full length) (ABIN7878639)

Antigène: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC16 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: OCA125-1900

Détail du produit anti-MUC16 anticorps

Épitope: full length

Fonction: MUC16 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Full length native MUC16 protein purified from human ovarian carcinoma was used as the immunogen for the MUC16 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the MUC16 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the MUC16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MUC16

Antigène: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Autre désignation: MUC16

Sujet: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

UniProt: Q8WXI7