MEF2D anticorps (full length)

N° du produit ABIN7878688

Cet anticorps anti-MEF2D Monoclonal Souris (Clone PCRP-MEF2D-3A4) (ABIN7878688) détecte spécifiquement MEF2D dans IHC (p), FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MEF2D anticorps (full length) (ABIN7878688)

Antigène: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MEF2D est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-MEF2D-3A4

Détail du produit anti-MEF2D anticorps

Épitope: full length

Fonction: MEF2D Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human MEF2D protein was used as the immunogen for the MEF2D antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the MEF2D antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MEF2D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MEF2D

Antigène: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Autre désignation: MEF2D

Sujet: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF4, are one class of identified factors. A second family of DNA-binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

UniProt: Q14814