PDLIM1 anticorps (full length)

N° du produit ABIN7878784

Cet anticorps anti-PDLIM1 Monoclonal Souris (Clone CPTC-PDLIM1-1) (ABIN7878784) détecte spécifiquement PDLIM1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PDLIM1 anticorps (full length) (ABIN7878784)

Antigène: PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDLIM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CPTC-PDLIM1-1

Détail du produit anti-PDLIM1 anticorps

Épitope: full length

Fonction: PDLIM1 Antibody

Purification: Protein G affinity chromatography

Immunogène: A recombinant human full-length PDLIM1 protein was used as the immunogen for this PDLIM1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the PDLIM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the PDLIM1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur PDLIM1

Antigène: PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))

Autre désignation: PDLIM1

Sujet: CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88 % sequence similarity with its rat counterpart, suggesting a conserved function between species.

UniProt: O00151