Peroxiredoxin 4 anticorps (full length)

N° du produit ABIN7878792

L’anticorps anti-Peroxiredoxin 4 Monoclonal Souris est utilisé pour la détection de Peroxiredoxin 4 dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Peroxiredoxin 4 anticorps (full length) (ABIN7878792)

Antigène: Peroxiredoxin 4 (PRDX4)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Peroxiredoxin 4 est non-conjugé

Application: ELISA

Clone: CPTC-PRDX4-1

Détail du produit anti-Peroxiredoxin 4 anticorps

Épitope: full length

Fonction: Peroxiredoxin 4 Antibody / PRDX4

Purification: Protein G affinity

Immunogène: A recombinant full-length human PRDX4 protein was used as the immunogen for the Peroxiredoxin 4 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the Peroxiredoxin 4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the Peroxiredoxin 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Peroxiredoxin 4

Antigène: Peroxiredoxin 4 (PRDX4)

Autre désignation: Peroxiredoxin 4

Sujet: The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX IV gene is expressed in many tissues. It exists as a precursor protein, which is only detected in testis, and aprocessed secreted form. PRX IV is highly expressed in lung cancer and is necessary for the promotion of lung cancer in vitro. Studies have demonstrated that PRX IV positive expression is significantly correlated with recurrences and shorter disease-free survival in patients with early-stage lung squamous cell carcinoma, and therefore can be used as a prognostic marker in lung squamous cell carcinoma.

UniProt: Q13162