PBX2 anticorps (full length)

N° du produit ABIN7878838

Cet anticorps anti-PBX2 Monoclonal Souris (Clone PCRP-PBX2-1C4) (ABIN7878838) détecte spécifiquement PBX2 dans ELISA, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PBX2 anticorps (full length) (ABIN7878838)

Antigène: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PBX2 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-PBX2-1C4

Détail du produit anti-PBX2 anticorps

Épitope: full length

Fonction: PBX2 Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human PBX2 protein was used as the immunogen for the PBX2 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the PBX2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PBX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PBX2

Antigène: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Autre désignation: PBX2

Sujet: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development