Recombinant RPSA/Laminin Receptor anticorps (full length)

N° du produit ABIN7878925

Cet anticorps anti-RPSA/Laminin Receptor Monoclonal Lapin (Clone RPSA-6332R) (ABIN7878925) détecte spécifiquement RPSA/Laminin Receptor dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant RPSA/Laminin Receptor anticorps (full length) (ABIN7878925)

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RPSA/Laminin Receptor est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RPSA-6332R

Détail du produit anti-RPSA/Laminin Receptor anticorps

Épitope: full length

Fonction: 40S Ribosomal protein SA Antibody / RPSA / Laminin Receptor 1

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human RPSA protein was used as the immunogen for the 40S Ribosomal protein SA antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the 40S Ribosomal protein SA antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the 40S Ribosomal protein SA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur RPSA/Laminin Receptor

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Autre désignation: 40S Ribosomal protein SA

Sujet: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family member, 40S Ribosomal protein SA, also called Laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly