RBM8A anticorps (full length)

N° du produit ABIN7878928

Cet anticorps anti-RBM8A Monoclonal Souris (Clone PCRP-RBM8A-1B4) (ABIN7878928) détecte spécifiquement RBM8A dans WB, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RBM8A anticorps (full length) (ABIN7878928)

Antigène: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RBM8A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: PCRP-RBM8A-1B4

Détail du produit anti-RBM8A anticorps

Épitope: full length

Fonction: RBM8A/Y14 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human RBM8A protein was used as the immunogen for the RBM8A/Y14 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the RBM8A/Y14 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the RBM8A/Y14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur RBM8A

Antigène: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Autre désignation: RBM8A/Y14

Sujet: The exon junction complex (EJC) is a multiprotein complex that assembles approximately 20-24 nucleotides upstream of exon-exon junctions in pre-mRNAs. It is involved in mRNA export, cytoplasmic localization, and nonsense-mediated mRNA decay. Members of the EJC include Y14, Aly/REF, Magoh, RNPS1, SRm160, and DEK. Aly/REF, Magoh, and Y14, identified as RBM8 in mouse and rat, make up the core of the EJC, and these proteins remain stably bound to spliced mRNAs in the cytoplasm until they are translated. Therefore, Y14, Aly/REF, and Magoh have the ability to communicate to the cytoplasm the processing history of the mRNA, including the position of the removed introns. The gene encoding human Y14 encodes three transcripts. Y14 is a ubiquitously expressed protein. Although Y14 shuttles to the cytoplasm, it is predominantly detected in the nucleus and is co-localized with oskar mRNA at the posterior pole of the cell.

UniProt: Q9Y5S9