SRF anticorps (full length)

N° du produit ABIN7879006

Cet anticorps anti-SRF Monoclonal Souris (Clone PCRP-SRF-1F1) (ABIN7879006) détecte spécifiquement SRF dans WB, ELISA, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SRF anticorps (full length) (ABIN7879006)

Antigène: SRF (Serum Response Factor (SRF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SRF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: PCRP-SRF-1F1

Détail du produit anti-SRF anticorps

Épitope: full length

Fonction: SRF Antibody / Serum Response Factor (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human SRF protein was used as the immunogen for the SRF antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the SRF antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the SRF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SRF

Antigène: SRF (Serum Response Factor (SRF))

Autre désignation: SRF

Sujet: Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino-terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.

UniProt: P11831