SHBG anticorps (full length)

N° du produit ABIN7879018

Cet anticorps anti-SHBG Monoclonal Souris (Clone SPM605) (ABIN7879018) détecte spécifiquement SHBG dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SHBG anticorps (full length) (ABIN7879018)

Antigène: SHBG (Sex Hormone Binding Globulin (SHBG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SHBG est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM605

Détail du produit anti-SHBG anticorps

Épitope: full length

Fonction: SHBG Antibody

Purification: Protein G affinity chromatography

Immunogène: Recombinant full-length human protein was used as the immunogen for the SHBG antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the SHBG antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the SHBG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur SHBG

Antigène: SHBG (Sex Hormone Binding Globulin (SHBG))

Autre désignation: SHBG

Sujet: Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

UniProt: P04278

Pathways: Hormone Transport