NUMB anticorps (pSer276) (Biotin)

N° du produit ABIN744430

Cet anticorps Lapin Polyclonal détecte spécifiquement NUMB dans WB, ELISA et IHC (fro). Il présente une réactivité envers Souris.

Aperçu rapide pour NUMB anticorps (pSer276) (Biotin) (ABIN744430)

Antigène: NUMB (Numb Homolog (NUMB))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUMB est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-NUMB anticorps (Biotin)

Épitope: pSer276

Specificité: This phosphorylation site is homologous to that of Ser276 in Mouse and Ser275 in Rat.

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Numb around the phosphorylation site of Ser276

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur NUMB

Antigène: NUMB (Numb Homolog (NUMB))

Autre désignation: Numb

Sujet:

Synonyms: S171, C14orf41, c14_5527, Protein numb homolog, h-Numb, Protein S171, NUMB

Background: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

ID gène: 8650

UniProt: P49757

Pathways: Cell-Cell Junction Organization