SIRT2 anticorps (full length)

N° du produit ABIN7879049

Cet anticorps Souris Monoclonal détecte spécifiquement SIRT2 dans WB, IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SIRT2 anticorps (full length) (ABIN7879049)

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: PCRP-SIRT2-1A8

Détail du produit anti-SIRT2 anticorps

Épitope: full length

Fonction: Sirtuin 2 Antibody / SIRT2 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human SIRT2/Sirtuin 2 protein was used as the immunogen for the Sirtuin 2 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the Sirtuin 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Sirtuin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SIRT2

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Autre désignation: Sirtuin 2

Sujet: The silent information regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. In S. cerevisiae, Sir2p deacetylates histones in a NAD-dependent manner, which regulates silencing at the telomeric, rDNA and silent mating-type loci. Sir2p is the founding member of a large family, designated sirtuins, which contain a conserved catalytic domain. The human homologs, which include SIRT1-7, are divided into four main branches: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. SIRT proteins may function via mono-ADP-ribosylation of proteins. SIRT2 contains a 323 amino acid catalytic core domain with a NAD-binding domain and a large groove which is the likely site of catalysis.

UniProt: Q8IXJ6