SIRT2 anticorps (full length)

N° du produit ABIN7879050

L’anticorps anti-SIRT2 Monoclonal Souris est utilisé pour la détection de SIRT2 dans des échantillons de Humain. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour SIRT2 anticorps (full length) (ABIN7879050)

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-SIRT2-1A8

Détail du produit anti-SIRT2 anticorps

Épitope: full length

Fonction: Sirtuin 2 Antibody / SIRT2

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human SIRT2/Sirtuin 2 protein was used as the immunogen for the Sirtuin 2 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the Sirtuin 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Sirtuin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SIRT2

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Autre désignation: Sirtuin 2

Sujet: The silent information regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. In S. cerevisiae, Sir2p deacetylates histones in a NAD-dependent manner, which regulates silencing at the telomeric, rDNA and silent mating-type loci. Sir2p is the founding member of a large family, designated sirtuins, which contain a conserved catalytic domain. The human homologs, which include SIRT1-7, are divided into four main branches: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. SIRT proteins may function via mono-ADP-ribosylation of proteins. SIRT2 contains a 323 amino acid catalytic core domain with a NAD-binding domain and a large groove which is the likely site of catalysis.

UniProt: Q8IXJ6