Recombinant TCP1 alpha/CCTA anticorps (full length)

N° du produit ABIN7879123

Cet anticorps anti-TCP1 alpha/CCTA Monoclonal Lapin (Clone TMPR63-1R) (ABIN7879123) détecte spécifiquement TCP1 alpha/CCTA dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant TCP1 alpha/CCTA anticorps (full length) (ABIN7879123)

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TCP1 alpha/CCTA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: TMPR63-1R

Détail du produit anti-TCP1 alpha/CCTA anticorps

Épitope: full length

Fonction: Recombinant p63 Antibody / Rabbit Monoclonal (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogène: Full-length human recombinant protein was used as the immunogen for the recombinant p63 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the recombinant p63 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant p63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur TCP1 alpha/CCTA

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Autre désignation: p63

Sujet: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. [UniProt]

UniProt: Q9H3D4