Th-POK (full length) anticorps

N° du produit ABIN7879140

L’anticorps anti-Th-POK Monoclonal Souris est utilisé pour la détection de Th-POK dans des échantillons de Humain. Il a été validé pour FACS, IF et WB.

Aperçu rapide pour Th-POK (full length) anticorps (ABIN7879140)

Antigène: Th-POK

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

Clone: PCRP-ZBTB7B-1B6

Détail du produit

Épitope: full length

Fonction: Th-Pok Antibody / ZBTB7B

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human Zinc finger and BTB domain-containing protein 7B protein was used as the immunogen for the Th-Pok antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Th-Pok antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Th-Pok antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: Th-POK

Sujet: TH-POK (T-helper-inducing POZ/Kr ppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and Fibronectin.

UniProt: O15156