Cet anticorps anti-Thrombomodulin Monoclonal Lapin (Clone THBD-8188R) (ABIN7879141) détecte spécifiquement Thrombomodulin dans IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
THBD
Reactivité: Humain
WB, FACS, IF
Hôte: Lapin
Polyclonal
RB56919
unconjugated
Indications d'application
Optimal dilution of the CD141 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
-20 °C
Stockage commentaire
Aliquot the CD141 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
Thrombomodulin (THBD)
Autre désignation
CD141
Sujet
It recognizes a protein of 75 kDa, identified as Thrombomodulin, or CD141. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.