TGFB2 anticorps (full length)

N° du produit ABIN7879180

Cet anticorps anti-TGFB2 Monoclonal Souris (Clone TGFB2-1679) (ABIN7879180) détecte spécifiquement TGFB2 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TGFB2 anticorps (full length) (ABIN7879180)

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFB2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TGFB2-1679

Détail du produit anti-TGFB2 anticorps

Épitope: full length

Fonction: TGF beta 2 Antibody / TGFB2

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the TGF beta 2 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the TGF beta 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TGF beta 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur TGFB2

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Autre désignation: TGF beta 2

Sujet: Transforming growth factor Bs (TGFbs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFa. It is now realized that TGFbs mediate many cell-cell interactions that occur during embryonic development. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80 % identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.

UniProt: P10600

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus