Recombinant Transgelin anticorps (full length)

N° du produit ABIN7879181

Cet anticorps Souris Monoclonal détecte spécifiquement Transgelin dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Transgelin anticorps (full length) (ABIN7879181)

Antigène: Transgelin (TAGLN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transgelin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: RTAGLN-8975

Détail du produit anti-Transgelin anticorps

Épitope: full length

Fonction: Recombinant Transgelin Antibody / SM22 alpha (azide and preservative free)

Séquence: TAGLN

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human Transgelin (TAGLN) protein was used as the immunogen for the recombinant Transgelin antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Transgelin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Transgelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Transgelin

Antigène: Transgelin (TAGLN)

Autre désignation: Transgelin

Sujet: This mAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.

UniProt: Q01995