Recombinant Transgelin anticorps (full length)

N° du produit ABIN7879182

L’anticorps anti-Transgelin Monoclonal Souris est utilisé pour la détection de Transgelin dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant Transgelin anticorps (full length) (ABIN7879182)

Antigène: Transgelin (TAGLN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transgelin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RTAGLN-8975

Détail du produit anti-Transgelin anticorps

Épitope: full length

Fonction: Recombinant Transgelin Antibody / SM22 alpha

Séquence: TAGLN

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human Transgelin (TAGLN) protein was used as the immunogen for the recombinant Transgelin antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Transgelin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Transgelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Transgelin

Antigène: Transgelin (TAGLN)

Autre désignation: Transgelin

Sujet: This mAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.

UniProt: Q01995