Tumor Protein p73 anticorps (full length)
Aperçu rapide pour Tumor Protein p73 anticorps (full length) (ABIN7879266)
Antigène
Voir toutes Tumor Protein p73 (TP73) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- p73 Antibody (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogène
- A recombinant full-length human protein was used as the immunogen for this p73 antibody.
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal dilution of the p73 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the p73 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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Autre désignation
- p73
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Sujet
- The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.
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UniProt
- O15350
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Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
Antigène
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