Tyrosinase-Related Protein 1 anticorps (full length)
Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (full length) (ABIN7879272)
Antigène
Voir toutes Tyrosinase-Related Protein 1 (TYRP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
-
-
Épitope
- full length
-
Fonction
- TRP1 Antibody Cocktail / Tyrosinase-Related Protein-1 / TYRP1 (azide and preservative free)
-
Purification
- Protein A/G affinity
-
Immunogène
- SK-MEL-23 cells (clone TA99) and recombinant full-length human TYRP1 protein (clone TYRP1/807) were used as the immunogen for the TRP1 antibody cocktail.
-
Isotype
- IgG2a, kappa
-
-
-
-
Indications d'application
- Optimal dilution of the TRP1 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot the TRP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- Tyrosinase-Related Protein 1 (TYRP1)
-
Autre désignation
- TRP1
-
Sujet
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
-
UniProt
- P17643
Antigène
-