ZBTB46 anticorps (full length)

N° du produit ABIN7879349

Cet anticorps Souris Monoclonal détecte spécifiquement ZBTB46 dans WB, IF, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ZBTB46 anticorps (full length) (ABIN7879349)

Antigène: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZBTB46 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: PCRP-ZBTB46-2B8

Détail du produit anti-ZBTB46 anticorps

Épitope: full length

Fonction: ZBTB46 Antibody / BTBD4 / ZNF340 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human Zinc finger and BTB domain-containing protein 46 protein was used as the immunogen for the ZBTB46 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the ZBTB46 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the ZBTB46 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ZBTB46

Antigène: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Autre désignation: ZBTB46

Sujet: BTBD4 (BTB/POZ domain-containing protein 4), also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46), is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

UniProt: Q86UZ6