pan Keratin anticorps (pan) (PE)
Aperçu rapide pour pan Keratin anticorps (pan) (PE) (ABIN7879688)
Antigène
Voir toutes pan Keratin (panKRT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pan
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Fonction
- Pan Cytokeratin Antibody (PE Conjugate)
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Purification
- Protein A/G affinity
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Immunogène
- Human epidermal keratin was used as the immunogen for the Pan Cytokeratin antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the PE-conjugated Pan Cytokeratin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the PE-conjugated Pan Cytokeratin antibody in the dark at 2-8oC (do not freeze, conjugate is light sensitive).
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- pan Keratin (panKRT)
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Autre désignation
- Pan Cytokeratin
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Sujet
- Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. This MAb is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
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UniProt
- Q7Z794
Antigène
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