Recombinant pan Keratin anticorps (pan)

N° du produit ABIN7879696

Cet anticorps anti-pan Keratin Monoclonal Lapin (Clone MonoPoly-4999R) (ABIN7879696) détecte spécifiquement pan Keratin dans IF, FACS, WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant pan Keratin anticorps (pan) (ABIN7879696)

Antigène: pan Keratin (panKRT)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp pan Keratin est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MonoPoly-4999R

Détail du produit anti-pan Keratin anticorps

Épitope: pan

Fonction: Pan Cytokeratin Antibody Cocktail (Acidic + Basic)

Purification: Protein A/G affinity

Immunogène: Recombinant fragments and/or synthetic peptides of human Cytokeratin proteins were used as the immunogen for the Pan Cytokeratin antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Pan Cytokeratin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Pan Cytokeratin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur pan Keratin

Antigène: pan Keratin (panKRT)

Autre désignation: Pan Cytokeratin

Sujet: MonoPoly antibodies are designed by pooling several monospecific, recombinant monoclonal antibodies against a target. MonoPoly antibodies are a kind of synthetic polyclonal antibodies that can be produced in unlimited quantity with a strict lot-to-lot consistency. These antibodies are highly specific with exquisite sensitivity and a single MonoPoly antibody can be used for a variety of applications.

This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 55 kDa (CK7), 52 kDa (CK8), 56.5 kDa (CK10), 53 kDa (CK13), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), 46 kDa (CK17), 45 kDa (CK18), 40 kDa (CK19) and 46 kDa (CK20). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. This antibody is a broad-spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms.

UniProt: Q7Z794