ACP2 anticorps
Aperçu rapide pour ACP2 anticorps (ABIN7879861)
Antigène
Voir toutes ACP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- ACP2 Antibody / Lysosomal Acid Phosphatase
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Séquence
- RSLRFVTLLY RHGDRSPVKT YPKDPYQE
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Purification
- Antigen affinity purified
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Immunogène
- Amino acids RSLRFVTLLYRHGDRSPVKTYPKDPYQE were used as the immunogen for the ACP2 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the ACP2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the ACP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))
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Autre désignation
- ACP2
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Sujet
- Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.
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UniProt
- P11117
Antigène
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