ALPL anticorps

N° du produit ABIN7879951

Cet anticorps anti-ALPL Polyclonal Lapin (ABIN7879951) détecte spécifiquement ALPL dans WB, FACS, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ALPL anticorps (ABIN7879951)

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALPL est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ALPL anticorps

Fonction: ALPL Antibody / Tissue-nonspecific Alkaline Phosphatase

Séquence: KDPKYWRDQA QETLKYALEL Q

Purification: Affinity purified

Immunogène: Amino acids KDPKYWRDQAQETLKYALELQ from the human protein were used as the immunogen for the ALPL antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ALPL antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ALPL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ALPL

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Autre désignation: ALPL

Sujet: Alkaline phosphatase (ALPL) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH . Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. ALPL is the alkaline phosphatase of skin fibroblasts, the tissue-nonspecific type, and that it is active toward millimolar concentrations of the putative natural substrates phosphoethanolamine (PEA) and pyridoxal-5-prime-phosphate (PLP). ALPL gene exists in single copy in the haploid genome and is composed of 12 exons distributed over more than 50 kb. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.

UniProt: P05186