ALOX5 anticorps

N° du produit ABIN7879995

L’anticorps anti-ALOX5 Monoclonal Lapin est utilisé pour la détection de ALOX5 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour ALOX5 anticorps (ABIN7879995)

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ALOX5 est non-conjugé

Application: Western Blotting (WB)

Clone: AECE-1

Détail du produit anti-ALOX5 anticorps

Fonction: 5-Lipoxygenase Antibody / ALOX5

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human 5-Lipoxygenase / ALOX5 was used as the immunogen for the 5-Lipoxygenase antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the 5-Lipoxygenase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the 5-Lipoxygenase antibody at -20oC.

Détails sur ALOX5

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Autre désignation: 5-Lipoxygenase

Sujet: The ALOX5 gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. [RefSeq]

UniProt: P09917