ABCA4
Reactivité: Humain, Singe
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the ABCA4 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
0.5 mg/mL in 1X TBS, pH 7.3, with 0.5 % BSA (US sourced) and 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Aliquot and store the ABCA4 antibody at -20oC.
Antigène
ABCA4
(ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
Autre désignation
ABCA4
Sujet
The ABCA4 protein is a transporter molecule responsible for moving retinal molecules across cell membranes in the eye and may have a broader impact on neurological processes. Research has shown that this protein is not restricted to the eyes, but is also present in various regions of the brain. ABCA4 plays a role in the maintenance of lipid homeostasis in the central nervous system. Lipids are essential components of cell membranes and are crucial for neuronal function. Disruptions in lipid metabolism have been implicated in numerous neurological disorders, including Alzheimer's disease and Parkinson's disease. ABCA4 has been found to interact with other proteins involved in synaptic transmission and neuronal signaling. This suggests that the protein may play a role in modulating communication between neurons, which is essential for cognitive function.