BCAM anticorps

N° du produit ABIN7880052

L’anticorps anti-BCAM Polyclonal Lapin est utilisé pour la détection de BCAM dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, FACS, IF et IHC (p).

Aperçu rapide pour BCAM anticorps (ABIN7880052)

Antigène: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAM est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BCAM anticorps

Fonction: BCAM Antibody / CD239

Séquence: LLSLTSTLYL RLRKDDRDAS FHCAAHYSLP EGRH

Purification: Affinity purified

Immunogène: Amino acids LLSLTSTLYLRLRKDDRDASFHCAAHYSLPEGRH from the human protein were used as the immunogen for the BCAM antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the BCAM antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the BCAM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur BCAM

Antigène: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Autre désignation: BCAM

Sujet: Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membraneglycoprotein that in humans is encoded by the BCAM gene. It is mapped to 19q13.32. This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P50895