CEA anticorps

N° du produit ABIN7880177

Cet anticorps Souris Monoclonal détecte spécifiquement CEA dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CEA anticorps (ABIN7880177)

Antigène: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM584

Détail du produit anti-CEA anticorps

Fonction: CEA Antibody / CEACAM5

Purification: Protein G affinity chromatography

Immunogène: Human colon carcinoma extract was used as the immunogen for this CEA antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: The optimal dilution of the CEA antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CEA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CEA

Antigène: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Autre désignation: CEA

Sujet: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This mAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

UniProt: P06731