Cathepsin B anticorps

N° du produit ABIN7880201

Cet anticorps Lapin Monoclonal détecte spécifiquement Cathepsin B dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cathepsin B anticorps (ABIN7880201)

Antigène: Cathepsin B (CTSB)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin B est non-conjugé

Application: Western Blotting (WB)

Clone: AAFO-3

Détail du produit anti-Cathepsin B anticorps

Fonction: CTSB Antibody / Cathepsin B

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Cathepsin B / CTSB was used as the immunogen for the CTSB antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CTSB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the CTSB antibody at -20oC.

Détails sur Cathepsin B

Antigène: Cathepsin B (CTSB)

Autre désignation: CTSB

Sujet: The CTSB gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. [RefSeq]

UniProt: P07858

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades