Cathepsin L anticorps

N° du produit ABIN7880208

L’anticorps anti-Cathepsin L Polyclonal Lapin est utilisé pour la détection de Cathepsin L dans des échantillons de Souris et Rat. Il a été validé pour WB, IHC (p) et FACS.

Aperçu rapide pour Cathepsin L anticorps (ABIN7880208)

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Cathepsin L anticorps

Fonction: Cathepsin L Antibody / Ctsl

Séquence: KYRAEFAVAN DTGFVDIPQQ

Purification: Antigen affinity purified

Immunogène: Amino acids KYRAEFAVANDTGFVDIPQQ from the mouse protein were used as the immunogen for the Cathepsin L antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cathepsin L antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Cathepsin L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: Cathepsin L

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell.

UniProt: P06797

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades