CEBPE anticorps
Aperçu rapide pour CEBPE anticorps (ABIN7880217)
Antigène
Voir toutes CEBPE AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- C/EBP epsilon Antibody / CEBPE (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant human protein was used as the immunogen for the C/EBP epsilon antibody.
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Isotype
- IgG2a
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Indications d'application
- Optimal dilution of the C/EBP epsilon antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the C/EBP epsilon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CEBPE (CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))
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Autre désignation
- C/EBP epsilon
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Sujet
- The transcription factor C/EBP Alpha (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP Alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic Alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP Alpha appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP beta, C/EBP gamma, C/EBP delta and C/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C/EBP Alpha. Furthermore, C/EBP beta and C/EBP delta readily form heterodimers both with each other as well as with C/EBP Alpha.
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UniProt
- Q15744
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
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