Cet anticorps anti-CEBPE Monoclonal Souris (Clone PCRP-CEBPE-1G12) (ABIN7880218) détecte spécifiquement CEBPE dans IF et FACS.
L’anticorps est réactif avec des échantillons de Humain.
CEBPE
Reactivité: Humain
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the C/EBP epsilon antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the C/EBP epsilon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
CEBPE
(CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))
Autre désignation
C/EBP epsilon
Sujet
The transcription factor C/EBP Alpha (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP Alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic Alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP Alpha appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP beta, C/EBP gamma, C/EBP delta and C/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C/EBP Alpha. Furthermore, C/EBP beta and C/EBP delta readily form heterodimers both with each other as well as with C/EBP Alpha.