DC-SIGN/CD209 anticorps
Aperçu rapide pour DC-SIGN/CD209 anticorps (ABIN7880257)
Antigène
Voir toutes DC-SIGN/CD209 (CD209) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- CD209 Antibody / DC-SIGN
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Purification
- Protein A/G affinity
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Immunogène
- A recombinant human DC-SIGN/CD209 protein fragment was used as the immunogen for the CD209 antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the CD209 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the CD209 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DC-SIGN/CD209 (CD209) (CD209)
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Autre désignation
- CD209
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Sujet
- DC-SIGN/CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
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UniProt
- Q9NNX6
Antigène
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