Recombinant DC-SIGN/CD209 anticorps

N° du produit ABIN7880259

L’anticorps anti-DC-SIGN/CD209 Monoclonal Souris est utilisé pour la détection de DC-SIGN/CD209 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant DC-SIGN/CD209 anticorps (ABIN7880259)

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DC-SIGN/CD209 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RC209-1781

Détail du produit anti-DC-SIGN/CD209 anticorps

Fonction: Recombinant CD209 Antibody / DC-SIGN

Purification: Protein G affinity chromatography

Immunogène: A human recombinant partial protein was used as the immunogen for this recombinant CD209 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CD209 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant CD209 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur DC-SIGN/CD209

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Autre désignation: CD209

Sujet: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

UniProt: Q9NNX6