CD45RB anticorps

N° du produit ABIN7880315

Cet anticorps Lapin Polyclonal détecte spécifiquement CD45RB dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD45RB anticorps (ABIN7880315)

Antigène: CD45RB

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD45RB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD45RB anticorps

Fonction: CD45RB Antibody

Purification: Protein A affinity chromatography

Immunogène: Human CD45RB protein was used as the immunogen for the CD45RB antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CD45RB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD45RB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CD45RB

Antigène: CD45RB

Autre désignation: CD45RB

Sujet: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

UniProt: P08575