CD46 anticorps

N° du produit ABIN7880328

L’anticorps anti-CD46 Monoclonal Lapin est utilisé pour la détection de CD46 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour CD46 anticorps (ABIN7880328)

Antigène: CD46

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AEI-3

Détail du produit anti-CD46 anticorps

Fonction: CD46 Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human CD46 was used as the immunogen for the CD46 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CD46 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the CD46 antibody at -20oC.

Détails sur CD46

Antigène: CD46

Autre désignation: CD46

Sujet: The protein encoded by the CD46 gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. [RefSeq]

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization