CENPB anticorps

N° du produit ABIN7880385

L’anticorps anti-CENPB Polyclonal Lapin est utilisé pour la détection de CENPB dans des échantillons de Humain. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour CENPB anticorps (ABIN7880385)

Antigène: CENPB (Centromere Protein B (CENPB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPB est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-CENPB anticorps

Fonction: CENPB Antibody / Centromere protein B

Séquence: HLEHDLVHVT RKNHA

Purification: Antigen affinity purified

Immunogène: Amino acids HLEHDLVHVTRKNHA from the human protein were used as the immunogen for the CENPB antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CENPB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CENPB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CENPB

Antigène: CENPB (Centromere Protein B (CENPB))

Autre désignation: CENPB

Sujet: Centromere protein B also known as major centromere autoantigen B is an autoantigen protein of the cell nucleus. In humans, centromere protein B is encoded by the CENPB gene. This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.

UniProt: P07199