Recombinant CHMP2B anticorps

N° du produit ABIN7880390

Cet anticorps Lapin Monoclonal détecte spécifiquement CHMP2B dans WB, IHC (p) et IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CHMP2B anticorps (ABIN7880390)

Antigène: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CHMP2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Clone: 25C36

Détail du produit anti-CHMP2B anticorps

Fonction: CHMP2B Antibody / Charged multivesicular body protein 2b

Purification: Affinity chromatography

Immunogène: A peptide sequence specific to Charged multivesicular body protein 2b protein was used as the immunogen for the CHMP2B antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CHMP2B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CHMP2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CHMP2B

Antigène: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Autre désignation: CHMP2B

Sujet: Charged multivesicular body protein 2b (CHMP2B) is a component of the endosomal sorting complex required for transport III (ESCRT-III). It plays a critical role in multivesicular body formation, membrane fission, and the sorting of ubiquitinated proteins for lysosomal degradation. CHMP2B is essential for maintaining proper endosomal trafficking and cellular protein homeostasis.

Mutations in CHMP2B have been linked to neurodegenerative disorders, including frontotemporal dementia and amyotrophic lateral sclerosis. Research on CHMP2B helps elucidate mechanisms of vesicular transport, neuronal maintenance, and protein quality control, making it relevant in both basic and disease-focused studies.

Using a high-quality CHMP2B antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A CHMP2B antibody from NSJ Bioreagents provides reliable and reproducible performance for studies in membrane trafficking, neurodegeneration, and cellular signaling. Selecting the right CHMP2B antibody is essential for obtaining consistent and meaningful results.

UniProt: Q9UQN3