CHI3L2 anticorps

N° du produit ABIN7880406

L’anticorps anti-CHI3L2 Monoclonal Souris est utilisé pour la détection de CHI3L2 dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour CHI3L2 anticorps (ABIN7880406)

Antigène: CHI3L2 (Chitinase 3-Like 2 (CHI3L2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CHI3L2 est non-conjugé

Application: ELISA

Clone: 1B2-G4

Détail du produit anti-CHI3L2 anticorps

Fonction: CHI3L2 Antibody / Chitinase 3 like 2 / YKL-39

Purification: Protein G affinity

Immunogène: A recombinant YKL-39 partial protein was used as the immunogen for the CHI3L2 antibody.

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal dilution of the CHI3L2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CHI3L2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CHI3L2

Antigène: CHI3L2 (Chitinase 3-Like 2 (CHI3L2))

Autre désignation: CHI3L2

Sujet: The CHI3L2 protein, also known as chitinase-3-like protein 2, is a glycoprotein that belongs to the chitinase protein family. It is primarily associated with various biological processes, including inflammation, tissue remodeling, and immune responses. CHI3L2 is expressed in various tissues, such as the lungs, liver, and immune cells, suggesting its involvement in diverse physiological functions. CHI3L2 has been implicated in modulating immune responses and inflammatory processes. It is often associated with conditions characterized by inflammation, such as autoimmune diseases and certain cancers. The protein's precise mechanism of action is still under investigation, but it is believed to play a role in cell signaling and the regulation of cellular interactions within the immune system. HI3L2/YKL-39 has been explored as a biomarker in cancer diagnosis: Elevated levels of CHI3L2 in the serum or tissues have been investigated as potential biomarkers for cancer detection and prognosis. Monitoring CHI3L2 levels may aid in cancer diagnosis and assessment of disease progression. Inflammatory joint diseases, such as rheumatoid arthritis, have shown increased CHI3L2 expression. Detection of CHI3L2 levels in synovial fluid or blood may have diagnostic value in rheumatoid arthritis. CHI3L2/YKl-39 has also been explored as a biomarker for cardiovascular diseases. Elevated levels in the blood may indicate vascular inflammation and provide insights into cardiovascular risk.

UniProt: Q15782